Mallikarjuna
Tupakula

AI Researcher  ·  IFM, MBZUAI  ·  Silicon Valley

Working on improving model capabilities on science and mathematics at the Institute of Foundation Models. MS student at RIT, researching AI Safety, Multimodal Learning, and NeuroAI.

I'm an independent researcher at the intersection of AI Safety, AI for Science, Multimodal Learning, and NeuroAI. Currently at IFM, MBZUAI in Sunnyvale and finishing my MS at RIT (full merit scholarship), where I work with Prof. Ashique KhudaBukhsh.

Previously nearly four years as a full-time researcher at the Indian School of Business with Prof. Sumeet Kumar, leading to publications at NeurIPS, ACL, ASONAM, and INFORMS JoC. Recipient of the Kathuria Pre-Doctoral Scholarship.

"Karmanye vadhikaraste ma phaleshu kadachana" — Bhagavad Gita
AI Safety AI for Science Multimodal Learning NeuroAI Foundation Models
Mallikarjuna Tupakula
NeurIPS'25 FM4LS2025 Sole Author

Thin Bridges for Drug Text Alignment: Lightweight Contrastive Learning for Target Specific Drug Retrieval

Mallikarjuna Tupakula

Abstract

We investigate whether thin contrastive bridges — lightweight projection heads over frozen unimodal encoders — can align chemical and textual representations without full multimodal pretraining. Using ChEMBL mechanism pairs, we align ECFP4 fingerprints with biomedical sentence embeddings via dual linear projections. Scaffold-based evaluation shows non-trivial cross-modal alignment and strong within-target discrimination.

INFORMS Journal on Computing2025

Quantifying the Academic Quality of Children's Videos Using Machine Comprehension

S. Kumar, M. Tupakula, A. R. KhudaBukhsh

ASONAM2024

Anonymous Dissent in the Digital Age: A YouTube Dislikes Dataset

S. Dutta, M. Tupakula, S. Kumar, A. R. KhudaBukhsh

ACL Student Research Workshop2023

Gender Stereotyping in Popular Children's Videos

T. S. Roy, M. Tupakula, S. Kumar, A. KhudaBukhsh

Under Review — IEEE TKDE2025

LLMs for Rating the Language of Children's Videos on YouTube

S. Kumar, M. Tupakula, A. R. KhudaBukhsh

Revising — Nature Human Behaviour2025

Gender Biases and Stereotyping in Children's Videos: 100 Popular YouTube Kids Channels

S. Kumar, M. Tupakula, A. R. KhudaBukhsh

Working Paper2025 Sole Author

Do Vision Transformers and Convolutional Neural Networks Fit Together?

Mallikarjuna Tupakula

Mar 2026

Started research internship at IFM, MBZUAI in Silicon Valley, working on improving model capabilities on science and mathematics.

Dec 2025

Presented sole-author work at NeurIPS 2025 FM4LS Workshop in San Diego.